About RLS
What is restless legs syndrome?
Restless legs syndrome (RLS) is a sensorimotor disorder characterized by unpleasant sensations that occur primarily in the legs. These sensations lead to an overwhelming desire to move the affected limb in an effort to ease discomfort. The effects of RLS are associated with sleep disturbance, daytime exhaustion, and diminished quality of life. The essential criteria for RLS diagnosis are5:
- an urge to move the legs
- symptoms begin or worsen during periods of rest
- symptoms are relieved by movement
- symptoms are worse in the evening or night.
There are two types of RLS—primary and secondary.
Currently, the cause of primary RLS is unknown. Some research has shown that half of the time primary RLS can be traced to a family history.6 Secondary RLS only occurs as a result of an underlying medical condition such as iron deficiency, end-stage renal disease, pregnancy, or diabetes. MIRAPEX is not indicated for the treatment of secondary RLS.5,7
What are the symptoms of RLS?
While RLS symptoms can vary from patient to patient, they are generally described as burning, creeping, crawling, aching, tingling, or tugging sensations in the legs.5,7,8 These sensations often occur in the lower legs, deep inside the leg. These sensations can also occur in the feet, thighs, trunk, and arms.7 The typical discomfort of RLS begins or intensifies when inactive.5
MIRAPEX is now indicated for moderate-to-severe primary Restless Legs Syndrome.
MIRAPEX is now indicated for moderate-to-severe primary Restless Legs Syndrome. Learn more
Learn more about diagnosing and evaluating Restless Legs Syndrome (RLS)
Learn more about diagnosing and evaluating Restless Legs Syndrome (RLS)
IMPORTANT SAFETY INFORMATION ABOUT MIRAPEX: MIRAPEX tablets are indicated for the treatment of moderate-to-severe primary Restless Legs Syndrome (RLS).
MIRAPEX may cause patients to fall asleep without any warning, even while doing normal daily activities, such as driving. When taking MIRAPEX, hallucinations may occur and sometimes patients may feel dizzy, sweaty or nauseated upon standing up. The most common side effects in clinical trials for RLS were nausea, headache, and tiredness. Patients should talk with their doctor if they experience these problems.
Patients and caregivers should be informed that impulse control disorders/compulsive behaviors may occur while taking medicines, including pramipexole, to treat Parkinson's disease and RLS.
This information is intended for U.S. residents only. Products discussed herein may have different labeling in different countries.
Please see full Prescribing Information, including patient information.
