Understanding MIRAPEX
Some important things you should know about MIRAPEX.
The effectiveness of MIRAPEX in the treatment of moderate to severe primary RLS has been shown in 4 clinical trials. Clinical trials are research studies that test the safety and efficacy of a particular drug.
- MIRAPEX patients showed a significant improvement in the severity of their symptoms compared with patients given a placebo (pill with no active ingredients)
- MIRAPEX patients showed symptom improvements that continued for up to 9 months
MIRAPEX is cleared by the kidneys, and MIRAPEX is not expected to have interactions with other drugs metabolized by the liver. Talk to your doctor about what this may mean for your treatment.
How MIRAPEX works in your body.
MIRAPEX works by acting like dopamine to stimulate the nerve cells that control movement. MIRAPEX is rapidly absorbed, reaching peak concentrations in approximately 2 hours. And MIRAPEX has a well-established safety profile and has been shown to be well tolerated in patients with RLS who may have other common diseases.
MIRAPEX is generally well tolerated
Generally, people who take MIRAPEX tolerate it well. It is initially prescribed at a low dose and gradually increased to result in the most effective relief. The most commonly reported adverse events in RLS clinical trials for MIRAPEX versus placebo were:
MIRAPEX vs Placebo
- Nausea (16% vs 5%, respectively)
- Headache (16% vs 15%, respectively)
- Fatigue (9% vs 7%, respectively)
- Somnolence (6% vs 3%, respectively)
Please note that this is not a complete list of possible side effects. When taking MIRAPEX, hallucinations may occur, and sometimes you may feel dizzy, sweaty, or nauseated upon standing up. Your doctor or pharmacist can give you further information. Likewise, it is important to talk to your doctor if you experience any of these problems.
IMPORTANT SAFETY INFORMATION ABOUT MIRAPEX: MIRAPEX tablets are indicated for the treatment of moderate-to-severe primary Restless Legs Syndrome (RLS).
MIRAPEX may cause you to fall asleep without any warning, even while doing normal daily activities, such as driving. When taking MIRAPEX, hallucinations may occur and sometimes you may feel dizzy, sweaty or nauseated upon standing up. The most common side effects in clinical trials for RLS were nausea, headache, and tiredness. You should talk with your doctor if you experience these problems.
Patients and caregivers should be informed that impulse control disorders/compulsive behaviors may occur while taking medicines, including pramipexole, to treat Parkinson's disease and RLS.
This information is intended for U.S. residents only. Products discussed herein may have different labeling in different countries.
Please see full Prescribing Information, including patient information.
